Fully Human Single Domain Antibody Platform
Unlock the Power of GeniusAb™.
Your Gateway to Next-Generation Therapeutics!
Antibody Screening Platform
With our state-of-the-art fully human single domain antibody screening platform, we are at the forefront of therapeutic innovation.
Welcome to GeniusAb™
At our company, we have used genetic engineering techniques to develop GeniusAb™ mouse models for the generation of fully human single domain antibodies (sdAbs). GeniusAb™ mouse model enables us to generate high-quality, customized antibodies for various research, diagnostic, and therapeutic applications. Furthermore, we have established comprehensive single domain antibody screening platforms to provide a one-stop solution from single domain antibody preparation to screening.
SCREENING PLATFORMS
Surface Display Technology
Phage surface display technology enables the selection and screening of large libraries of sdAbs displayed on the surface of bacteriophages.
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Yeast cells can be easily manipulated, allowing for the introduction of additional genetic modifications to improve the binding characteristics or other properties of the displayed sdAb.
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Bacteria surface display involves the genetic fusion of sdAb variants to the surface proteins of bacteria. This allows the expression and display of sdAb variants on the outer membrane of the bacteria.
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Mammalian cell surface display allows for the screening of large and diverse sdAb libraries, facilitating the identification of sdAbs with high affinity and specificity.
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Ribosome and mRNA Display Technology involves the in vitro synthesis and display of sdAb variants using ribosomes and mRNA molecules.
Read MoreAdvantages of Fully Human sdAbs
Small Size and Good Penetration Ability
High Stability
High Affinity and Specificity
Strong Plasticity and Easy to Transform
Low Immunogenicity
No Humanized Required and Cost-effective Production
Application Areas
Molecular Imaging and Diagnostics
The unique properties of single domain antibodies, such as small size, excellent stability, and high affinity for target molecules, make them valuable tools for a variety of molecular imaging and diagnostic assays.
Structural Biology Research
Single domain antibodies can be used as crystallization chaperones and as probes in various structural biology techniques to reveal the complexity of protein structure and function and advance our understanding of biological processes at the molecular level.
Targeted Drug
Delivery
By designing single domain antibodies to target specific cell surface receptors or markers, they can be used to deliver drugs directly to the desired site of action, thereby improving therapeutic outcomes and facilitating personalized medicine.
Disease Therapy Development
The versatility and efficacy of single domain antibodies in disease treatment hold promise for the development of novel and targeted therapies across a wide range of diseases, including cancer, infectious diseases, autoimmune disorders, and more.
Expertise
Our team of experienced scientists and researchers is renowned for their expertise in the field.
Cutting-edge Technology
Our company leverages state-of-the-art technology and innovative approaches to single domain antibody development.
Customization
We understand that each client's needs are unique. That's why we offer a highly customizable single domain antibody development service.
Why Choose Us?
Our advanced platform and and comprehensive services position us as a trusted partner in the development of innovative therapeutic solutions. We are committed to providing customers with high-quality, customized single domain antibody solutions.